Welcome to our Days Inn Seneca hotel near Lake Keowee Marina, an affordable and inviting place to stay for your next South Carolina excursion. Located off Highway 123/76, our hotel is just minutes from great shopping, golf courses, and Oconee Medical Center. Start your morning with a free Daybreak continental breakfast and free newspaper at our hotel. Perks include ample parking for all vehicles and free WiFi to check lake conditions from your room. Enjoy our outdoor pool, business center, gym, and guest laundry. Guest rooms are accessible and come equipped with 40-inch flat screen TVs. Our hotel is close to several lakes in the region. Hit the water and enjoy a day of boating and fishing, or hike the trails to see waterfalls and wildlife. Visit the parks for picnicking, outdoor sports, and more. Shop and dine in historic downtown Seneca. Stay with us for quick access to Clemson University.